Fixation pattern analysis with microperimetry in nystagmus patients
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http://hdl.handle.net/10045/53455
Title: | Fixation pattern analysis with microperimetry in nystagmus patients |
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Authors: | Molina-Martín, Ainhoa | Piñero, David P. | Pérez Cambrodí, Rafael J. |
Research Group/s: | Grupo de Óptica y Percepción Visual (GOPV) |
Center, Department or Service: | Universidad de Alicante. Departamento de Óptica, Farmacología y Anatomía |
Keywords: | Microperimetry | Fixation pattern | Nystagmus |
Knowledge Area: | Óptica |
Issue Date: | Dec-2015 |
Publisher: | Elsevier |
Citation: | Canadian Journal of Ophthalmology. 2015, 50(6): 413-421. doi:10.1016/j.jcjo.2015.07.012 |
Abstract: | Objective: To assess the usefulness of microperimetry (MP) as an additional objective method for characterizing the fixation pattern in nystagmus. Design: Prospective study. Participants: Fifteen eyes of 8 subjects (age, 12–80 years) with nystagmus from the Lluís Alcanyís Foundation (University of Valencia, Spain) were included. Methods: All patients had a comprehensive ophthalmologic examination including a microperimetric examination (MAIA, CenterVue, Padova, Italy). The following microperimetric parameters were evaluated: average threshold (AT), macular integrity index (MI), fixating points within a circle of 1° (P1) and 2° of radius (P2), bivariate contour ellipse area (BCEA) considering 63% and 95% of fixating points, and horizontal and vertical axes of that ellipse. Results: In monocular conditions, 6 eyes showed a fixation classified as stable, 6 eyes showed a relatively unstable fixation, and 3 eyes showed an unstable fixation. Statistically significant differences were found between the horizontal and vertical components of movement (p = 0.001), as well as in their ranges (p < 0.001). Intereye comparison showed differences between eyes in some subjects, but only statistically significant differences were found in the fixation coordinates X and Y (p < 0.001). No significant intereye differences were found between microperimetric parameters. Between monocular and binocular conditions, statistically significant differences in the X and Y coordinates were found in all eyes (p < 0.02) except one. No significant differences were found between MP parameters for monocular or binocular conditions. Strong correlations of corrected distance visual acuity (CDVA) with AT (r = 0.812, p = 0.014), MI (r = –0.812, p = 0.014), P1 (r = 0.729, p = 0.002), horizontal diameter of BCEA (r = –0.700, p = 0.004), and X range (r = –0.722, p = 0.005) were found. Conclusions: MP seems to be a useful technology for the characterization of the fixation pattern in nystagmus, which seems to be related to the level of visual acuity achieved by the patient. |
URI: | http://hdl.handle.net/10045/53455 |
ISSN: | 0008-4182 (Print) | 1715-3360 (Online) |
DOI: | 10.1016/j.jcjo.2015.07.012 |
Language: | eng |
Type: | info:eu-repo/semantics/article |
Rights: | © 2015 Canadian Ophthalmological Society. Published by Elsevier Inc. |
Peer Review: | si |
Publisher version: | http://dx.doi.org/10.1016/j.jcjo.2015.07.012 |
Appears in Collections: | INV - GOPV - Artículos de Revistas |
Files in This Item:
File | Description | Size | Format | |
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2015_Molina_etal_CanJOphthalmol_final.pdf | Versión final (acceso restringido) | 1,87 MB | Adobe PDF | Open Request a copy |
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