Prenylated Flavonoids of the Moraceae Family: A Comprehensive Review of Their Biological Activities
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http://hdl.handle.net/10045/142625
Títol: | Prenylated Flavonoids of the Moraceae Family: A Comprehensive Review of Their Biological Activities |
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Autors: | Morante Carriel, Jaime | Živković, Suzana | Nájera, Hugo | Sellés-Marchart, Susana | Martínez Márquez, Ascensión | Martínez Esteso, María José | Obrebska, Anna | Samper-Herrero, Antonio | Bru-Martinez, Roque |
Grups d'investigació o GITE: | Proteómica y Genómica Funcional de Plantas |
Centre, Departament o Servei: | Universidad de Alicante. Departamento de Bioquímica y Biología Molecular y Edafología y Química Agrícola |
Paraules clau: | Flavonoids | Prenylated compounds | Moraceae family | Bioactivities |
Data de publicació: | 27-d’abril-2024 |
Editor: | MDPI |
Citació bibliogràfica: | Plants. 2024, 13(9): 1211. https://doi.org/10.3390/plants13091211 |
Resum: | Prenylated flavonoids (PFs) are natural flavonoids with a prenylated side chain attached to the flavonoid skeleton. They have great potential for biological activities such as anti-diabetic,anti-cancer, antimicrobial, antioxidant, anti-inflammatory, enzyme inhibition, and anti-Alzheimer’s effects. Medicinal chemists have recently paid increasing attention to PFs, which have become vital for developing new therapeutic agents. PFs have quickly developed through isolation and semi- or full synthesis, proving their high value in medicinal chemistry research. This review comprehensively summarizes the research progress of PFs, including natural PFs from the Moraceae family and their pharmacological activities. This information provides a basis for the selective design and optimization of multifunctional PF derivatives to treat multifactorial diseases. |
Patrocinadors: | This work has been supported by the Spanish Ministry of Science and Innovation, MCIN/AEI/10.13039/501100011033, ERDF A way of making Europe, and European Union NextGenerationEU/PRTR grants PID2020-113438RB-I00 and TED2021-129617B-I00, and Valencian Conselleria d’Innovació, Universitats, Ciencia y Societat Digital grant CIAICO/2021/167. This work was also supported by the Ministry of Education, Science and Technological Development of the Republic of Serbia (Contract No. 451-03-66/2024-03/200007). |
URI: | http://hdl.handle.net/10045/142625 |
ISSN: | 2223-7747 |
DOI: | 10.3390/plants13091211 |
Idioma: | eng |
Tipus: | info:eu-repo/semantics/article |
Drets: | © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
Revisió científica: | si |
Versió de l'editor: | https://doi.org/10.3390/plants13091211 |
Apareix a la col·lecció: | INV - Proteómica y Genómica Funcional de Plantas - Artículos de Revistas |
Arxius per aquest ítem:
Arxiu | Descripció | Tamany | Format | |
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Morante-Carriel_etal_2024_Plants.pdf | 1,25 MB | Adobe PDF | Obrir Vista prèvia | |
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