Morante Carriel, Jaime, Živković, Suzana, Nájera, Hugo, Sellés-Marchart, Susana, Martínez Márquez, Ascensión, Martínez Esteso, María José, Obrebska, Anna, Samper-Herrero, Antonio, Bru-Martinez, Roque
Prenylated Flavonoids of the Moraceae Family: A Comprehensive Review of Their Biological Activities
Plants. 2024, 13(9): 1211. https://doi.org/10.3390/plants13091211
URI: http://hdl.handle.net/10045/142625
DOI: 10.3390/plants13091211
ISSN: 2223-7747
Abstract: 
Prenylated flavonoids (PFs) are natural flavonoids with a prenylated side chain attached to the flavonoid skeleton. They have great potential for biological activities such as anti-diabetic,anti-cancer, antimicrobial, antioxidant, anti-inflammatory, enzyme inhibition, and anti-Alzheimer’s effects. Medicinal chemists have recently paid increasing attention to PFs, which have become vital for developing new therapeutic agents. PFs have quickly developed through isolation and semi- or full synthesis, proving their high value in medicinal chemistry research. This review comprehensively summarizes the research progress of PFs, including natural PFs from the Moraceae family and their pharmacological activities. This information provides a basis for the selective design and optimization of multifunctional PF derivatives to treat multifactorial diseases.
Keywords:Flavonoids, Prenylated compounds, Moraceae family, Bioactivities
MDPI
info:eu-repo/semantics/article