A Meta-analysis of Gut Microbiota in Children with Autism
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http://hdl.handle.net/10045/114724
| Title: | A Meta-analysis of Gut Microbiota in Children with Autism |
|---|---|
| Authors: | Andreo-Martínez, Pedro | Rubio-Aparicio, María | Sánchez-Meca, Julio | Veas, Alejandro | Martínez-González, Agustín Ernesto |
| Research Group/s: | Psicología Aplicada a la Salud y Comportamiento Humano (PSYBHE) | Habilidades, Competencias e Instrucción | Grupo de Investigación Integral en el Neurodesarrollo Típico y Atípico (GINTA) |
| Center, Department or Service: | Universidad de Alicante. Departamento de Psicología de la Salud | Universidad de Alicante. Departamento de Psicología Evolutiva y Didáctica |
| Keywords: | Autism spectrum disorders (ASD) | Gut microbiota | Microbiota-gut-brain axis | Systematic review | Meta-analysis |
| Knowledge Area: | Personalidad, Evaluación y Tratamiento Psicológico | Psicología Evolutiva y de la Educación |
| Issue Date: | 5-May-2021 |
| Publisher: | Springer Nature |
| Citation: | Journal of Autism and Developmental Disorders. 2022, 52: 1374-1387. https://doi.org/10.1007/s10803-021-05002-y |
| Abstract: | Previous studies have reported dysbiosis in the gut microbiota (GM) of children with autism spectrum disorders (ASD), which may be a determining factor on child development through the microbiota-gut-brain axis. However, it is not clear if there is a specific group of dysbiotic bacteria in ASD. The aim of this study was to carry out a meta-analysis on the studies that analyze GM in children with ASD. 18 studies fulfilled our selection criteria. Our results showed a lower relative abundance of Streptococcus (SMD+ = − 0.999; 95% CI − 1.549, − 0.449) and Bifidobacterium genera (SMD+ = − 0.513; 95% CI − 0.953, − 0.073) in children with ASD. Overall, the Bifidobacterium genera is involved. However, differences found between studies are attributed to factors such as reporting bias. |
| URI: | http://hdl.handle.net/10045/114724 |
| ISSN: | 0162-3257 (Print) | 1573-3432 (Online) |
| DOI: | 10.1007/s10803-021-05002-y |
| Language: | eng |
| Type: | info:eu-repo/semantics/article |
| Rights: | © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021 |
| Peer Review: | si |
| Publisher version: | https://doi.org/10.1007/s10803-021-05002-y |
| Appears in Collections: | INV - GINTA - Artículos de Revistas INV - PSYBHE - Artículos de Revistas INV - Habilidades, Competencias e Instrucción - Artículos de Revistas |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
 Andreo-Martinez_etal_2021_JAutismDevDisord_posprint.pdf | Versión revisada (acceso abierto) | 566,3 kB | Adobe PDF | Open Preview |
 Andreo-Martinez_etal_2021_JAutismDevDisord_final.pdf | Versión final (acceso restringido) | 869,45 kB | Adobe PDF | Open Request a copy |
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