Kowalska, Malgorzata A., Kasprzak, Henryk T., Iskander, D. Robert, Danielewska, Monika, Mas, David Ultrasonic in vivo measurement of ocular surface expansion KOWALSKA, Malgorzata A., et al. “Ultrasonic in vivo measurement of ocular surface expansion”. IEEE Transactions on Biomedical Engineering. Vol. 58, No. 3 (March 2011). ISSN 0018-9294, pp. 674-680 URI: http://hdl.handle.net/10045/16672 DOI: 10.1109/TBME.2010.2100819 ISSN: 0018-9294 (Print) Abstract: Our aim was to ascertain whether the ultrasonic measurement of longitudinal corneal apex displacements carried out in a proper headrest is a credible method of ocular pulse (OP) detection. To distinguish between longitudinal movements of the eye globe treated as a rigid body and ocular surface expansion caused by the variations of the eye-globe volume, two ultrasound distance sensors were applied to noninvasively measure displacements of cornea and sclera. The same sensors were used to examine the influence of the anterio–posterior movements of a fixed head on the registration of corneal apex pulsation. In both experiments, ECG signals were synchronically recorded. Time, spectral, and coherence analyses obtained for four healthy subjects showed that the ocular surface expansion due to pulsatile ocular blood flow (POBF) is the main component of longitudinal corneal displacement. Ocular surface pulsation is always affected by the head movement. However, there exist some unique properties of signals, which help to distinguish between head and eye movements. A rigid headrest and a bite bar are required to stabilize the head during OP measurement. Ultrasonic technique enables noninvasive and accurate in vivo measurement of corneal pulsation, which could be of interest for indirectly estimating intraocular pressure propagation and POBF component. Keywords:ECG, Head-eye movement, Ocular pulse (OP), Spectral analysis IEEE info:eu-repo/semantics/article