Navarro-Calvo, Jorge, Esquiva, Gema, Gómez-Vicente, Violeta, Valor, Luis M.
MicroRNAs in the Mouse Developing Retina
Navarro-Calvo J, Esquiva G, Gómez-Vicente V, Valor LM. MicroRNAs in the Mouse Developing Retina. International Journal of Molecular Sciences. 2023; 24(3):2992. https://doi.org/10.3390/ijms24032992
URI: http://hdl.handle.net/10045/132665
DOI: 10.3390/ijms24032992
ISSN: 1422-0067
Abstract: 
The retina is among the highest organized tissues of the central nervous system. To achieve such organization, a finely tuned regulation of developmental processes is required to form the retinal layers that contain the specialized neurons and supporting glial cells to allow precise phototransduction. MicroRNAs are a class of small RNAs with undoubtful roles in fundamental biological processes, including neurodevelopment of the brain and the retina. This review provides a short overview of the most important findings regarding microRNAs in the regulation of retinal development, from the developmental-dependent rearrangement of the microRNA expression program to the key roles of particular microRNAs in the differentiation and maintenance of retinal cell subtypes.
Keywords:Retina, Mouse, Dicer, miR-183/96/182, miR-204/211, miR-124, miR-9, let-7, Transcriptomics
MDPI
info:eu-repo/semantics/article