A Bipyridine‐Palladium Derivative as General Pre‐Catalyst for Cross‐Coupling Reactions in Deep Eutectic Solvents
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http://hdl.handle.net/10045/95433
Title: | A Bipyridine‐Palladium Derivative as General Pre‐Catalyst for Cross‐Coupling Reactions in Deep Eutectic Solvents |
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Authors: | Saavedra, Beatriz | González-Gallardo, Nerea | Meli, Alessandro | Ramón, Diego J. |
Research Group/s: | Alternative Methodologies In Chemistry (AMIC) | Nuevos Materiales y Catalizadores (MATCAT) |
Center, Department or Service: | Universidad de Alicante. Departamento de Química Orgánica | Universidad de Alicante. Instituto Universitario de Síntesis Orgánica |
Keywords: | Cross-coupling | Green chemistry | Hydrogen bonds | Ligand design | Palladium |
Knowledge Area: | Química Orgánica |
Issue Date: | 21-Aug-2019 |
Publisher: | Wiley-VCH Verlag GmbH & Co. KGaA |
Citation: | Advanced Synthesis and Catalysis. 2019, 361(16): 3868-3879. doi:10.1002/adsc.201900472 |
Abstract: | A versatile and DES‐compatible bipyridine palladium complex has been developed as a general pre‐catalyst for different cross‐coupling reactions (Hiyama, Suzuki‐Miyaura, Heck‐Mizoroki and Sonogashira) in deep eutectic solvents. Hydrogen bond capacity of the ligand allows to keep the excellent level of results previously obtained in classical organic solvents. Palladium pre‐catalyst showed a high catalytic activity for many cross‐coupling reactions, demonstrating a great versatility and applicability. Also, this methodology employs sustainable solvents as a reaction medium and highlights the potential of DES as alternative solvents in organometallic catalysis. The catalyst and DES were easily and successfully recycled. The formation of PdNPs in DES has been confirmed by TEM and XPS analysis and their role as catalyst by mercury test. The dynamic coordination of bipyridine‐type ligand in the palladium complex formation has been studied via UV/Vis. |
Sponsor: | This work was supported by the University of Alicante (VIGROB-316) and the Spanish Ministerio de Economia, Industria y Competitividad (CTQ2015-66624-P, PGC2018-096616-B-100). BS thanks Generalitat Valenciana (ACIF/2017/211) for a fellowship. |
URI: | http://hdl.handle.net/10045/95433 |
ISSN: | 1615-4150 (Print) | 1615-4169 (Online) |
DOI: | 10.1002/adsc.201900472 |
Language: | eng |
Type: | info:eu-repo/semantics/article |
Rights: | © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim |
Peer Review: | si |
Publisher version: | https://doi.org/10.1002/adsc.201900472 |
Appears in Collections: | INV - AMIC - Artículos de Revistas INV - MATCAT - Artículos de Revistas |
Files in This Item:
File | Description | Size | Format | |
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2019_Saavedra_etal_AdvSynthCatal_final.pdf | Versión final (acceso restringido) | 2,84 MB | Adobe PDF | Open Request a copy |
2019_Saavedra_etal_AdvSynthCatal_accepted.pdf | Accepted Manuscript (acceso abierto) | 2,15 MB | Adobe PDF | Open Preview |
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