Effects of pomegranate juice in circulating parameters, cytokines, and oxidative stress markers in endurance-based athletes: A randomized controlled trial
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Campo DC | Valor | Idioma |
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dc.contributor | Grupo de Inmunología | es |
dc.contributor.author | Fuster-Muñoz, Encarnación | - |
dc.contributor.author | Roche, Enrique | - |
dc.contributor.author | Funes, Lorena | - |
dc.contributor.author | Martínez-Peinado, Pascual | - |
dc.contributor.author | Sempere Ortells, José Miguel | - |
dc.contributor.author | Vicente Salar, Nestor | - |
dc.contributor.other | Universidad de Alicante. Departamento de Biotecnología | es |
dc.date.accessioned | 2016-04-06T12:13:32Z | - |
dc.date.available | 2016-04-06T12:13:32Z | - |
dc.date.issued | 2016-05 | - |
dc.identifier.citation | Nutrition. 2016, 32(5): 539-545. doi:10.1016/j.nut.2015.11.002 | es |
dc.identifier.issn | 0899-9007 (Print) | - |
dc.identifier.issn | 1873-1244 (Online) | - |
dc.identifier.uri | http://hdl.handle.net/10045/54050 | - |
dc.description.abstract | Objective: The aim of the present study was to assess the effects of pomegranate juice on the level of oxidative stress in the blood of endurance-based athletes. Pomegranate juice is rich in polyphenols, conferring it a higher antioxidant capacity than other beverages with polyphenolic antioxidants. Methods: A randomized double-blind, multicenter trial was performed in athletes from three different sport clubs located in southeastern of Spain. Plasma oxidative stress markers (protein carbonyls and malondialdehyde [MDA]) as well as C-reactive protein and sE-selectin were measured. Thirty-one athletes participated in the study. Participants were divided into three groups. The first group was supplemented with 200 mL/d pomegranate juice (PJ; n = 10) over a 21-d period, the second with 200 mL/d pomegranate juice diluted 1:1 with water (PJD; n = 11), and a control group that did not consume pomegranate juice (C; n = 10). Nine athletes were excluded due to protocol violations (n = 4 in the PJ group and n = 5 in the PJD group) because they did not observe the 24 h of rest before the last blood test. Results: The control group increased levels of carbonyls (+0.7 ± 0.3 nmols/mg protein) and MDA (+3.2 ± 1.0 nmols/g protein), whereas the PJ and PJD groups maintained or decreased their levels, respectively. On the other hand, lactate levels increased in the PJ group (from 10.3 at day 0 to 21.2 mg/dL at day 22). A nonsignificant decrease was detected in sE-selectin and C-reactive protein in the groups consuming pomegranate juice. Conclusion: Consumption of pomegranate juice over a 21-d period improved MDA levels and carbonyls, and thus decreased the oxidative damage caused by exercise. | es |
dc.description.sponsorship | This research received specific grant and provision of supplements from Vitalgrana SL. The following institutions are acknowledged PROMETEO/2012/007 from Generalitat Valenciana and CIBEROBN (Fisiopatología de la Obesidad y la Nutrición CB12/03/30038) Instituto de Salud Carlos III, Spain to E Roche. | es |
dc.language | eng | es |
dc.publisher | Elsevier | es |
dc.rights | © 2016 Elsevier Inc. | es |
dc.subject | Pomegranate juice | es |
dc.subject | Antioxidants | es |
dc.subject | Sport | es |
dc.subject | Carbonyls | es |
dc.subject | Malondialdehyde | es |
dc.subject.other | Inmunología | es |
dc.title | Effects of pomegranate juice in circulating parameters, cytokines, and oxidative stress markers in endurance-based athletes: A randomized controlled trial | es |
dc.type | info:eu-repo/semantics/article | es |
dc.peerreviewed | si | es |
dc.identifier.doi | 10.1016/j.nut.2015.11.002 | - |
dc.relation.publisherversion | http://dx.doi.org/10.1016/j.nut.2015.11.002 | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
Aparece en las colecciones: | INV - Grupo de Inmunología - Artículos de Revistas |
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2016_Fuster_etal_Nutrition_final.pdf | Versión final (acceso restringido) | 571,11 kB | Adobe PDF | Abrir Solicitar una copia |
2016_Fuster_etal_Nutrition_accepted.pdf | Accepted Manuscript (acceso abierto) | 725,2 kB | Adobe PDF | Abrir Vista previa |
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