Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes

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Title: Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes
Authors: Nájera, Carmen | Sansano, Jose M.
Research Group/s: Síntesis Asimétrica (SINTAS)
Center, Department or Service: Universidad de Alicante. Departamento de Química Orgánica | Universidad de Alicante. Instituto Universitario de Síntesis Orgánica
Keywords: Antitumoral | Asymmetric synthesis | Catalysis | Cycloaddition | Metal | Organocatalyst
Knowledge Area: Química Orgánica
Issue Date: 2014
Publisher: Bentham Science Publishers
Citation: Current Topics in Medicinal Chemistry. 2014, 14(10): 1271-1282. doi:10.2174/1568026614666140423112145
Abstract: This review highlights the biological importance of many polysubstituted nitro-prolines and -pyrrolidines. Their preparation using asymmetric 1,3-dipolar cycloadditions of azomethine ylides with nitroalkenes using diastereoselective and enantioselective strategies is described remarking the scope and main features of each one.
Sponsor: This work has been supported by the Spanish Ministerio de Economía y Competitividad (MINECO) (Consolider INGENIO 2010 CSD2007-00006, CTQ2010-20387), FEDER, Generalitat Valenciana (PROMETEO/2009/039), and by the University of Alicante.
URI: http://hdl.handle.net/10045/37876
ISSN: 1568-0266 (Print) | 1873-5294 (Online)
DOI: 10.2174/1568026614666140423112145
Language: eng
Type: info:eu-repo/semantics/article
Rights: © 2014 Bentham Science Publishers
Peer Review: si
Publisher version: http://dx.doi.org/10.2174/1568026614666140423112145
Appears in Collections:INV - SINTAS - Artículos de Revistas

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