Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes
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Title: | Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes |
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Authors: | Nájera, Carmen | Sansano, Jose M. |
Research Group/s: | Síntesis Asimétrica (SINTAS) |
Center, Department or Service: | Universidad de Alicante. Departamento de Química Orgánica | Universidad de Alicante. Instituto Universitario de Síntesis Orgánica |
Keywords: | Antitumoral | Asymmetric synthesis | Catalysis | Cycloaddition | Metal | Organocatalyst |
Knowledge Area: | Química Orgánica |
Issue Date: | 2014 |
Publisher: | Bentham Science Publishers |
Citation: | Current Topics in Medicinal Chemistry. 2014, 14(10): 1271-1282. doi:10.2174/1568026614666140423112145 |
Abstract: | This review highlights the biological importance of many polysubstituted nitro-prolines and -pyrrolidines. Their preparation using asymmetric 1,3-dipolar cycloadditions of azomethine ylides with nitroalkenes using diastereoselective and enantioselective strategies is described remarking the scope and main features of each one. |
Sponsor: | This work has been supported by the Spanish Ministerio de Economía y Competitividad (MINECO) (Consolider INGENIO 2010 CSD2007-00006, CTQ2010-20387), FEDER, Generalitat Valenciana (PROMETEO/2009/039), and by the University of Alicante. |
URI: | http://hdl.handle.net/10045/37876 |
ISSN: | 1568-0266 (Print) | 1873-5294 (Online) |
DOI: | 10.2174/1568026614666140423112145 |
Language: | eng |
Type: | info:eu-repo/semantics/article |
Rights: | © 2014 Bentham Science Publishers |
Peer Review: | si |
Publisher version: | http://dx.doi.org/10.2174/1568026614666140423112145 |
Appears in Collections: | INV - SINTAS - Artículos de Revistas |
Files in This Item:
File | Description | Size | Format | |
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06-Nájera-MS.pdf | Versión revisada (acceso abierto) | 2,26 MB | Adobe PDF | Open Preview |
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