Repeated sequence homogenization between the control and pseudo-control regions in the mitochondrial genomes of the subfamily Aquilinae
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Título: | Repeated sequence homogenization between the control and pseudo-control regions in the mitochondrial genomes of the subfamily Aquilinae |
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Autor/es: | Cadahía Lorenzo, Luis | Pinsker, Wilhelm | Negro Balmaseda, Juan José | Pavlicev, Mihaela | Urios, Vicente | Haring, Elisabeth |
Grupo/s de investigación o GITE: | Zoología de Vertebrados |
Centro, Departamento o Servicio: | Universidad de Alicante. Departamento de Ciencias Ambientales y Recursos Naturales |
Palabras clave: | Mitochondrial genomes | Raptors | Aquilinae | Control region | Pseudo-control region | Homogenization |
Área/s de conocimiento: | Zoología |
Fecha de publicación: | 9-feb-2009 |
Editor: | Wiley-Liss, Inc. |
Cita bibliográfica: | CADAHÍA, Luis, et al. "Repeated sequence homogenization between the control and pseudo-control regions in the mitochondrial genomes of the subfamily Aquilinae". Journal of Experimental Zoology Part B: Molecular and Developmental Evolution. Vol. 312B, Issue 3 (15 May 2009). ISSN 1552-5007, pp. 171-185 |
Resumen: | In birds, the noncoding control region (CR) and its flanking genes are the only parts of the mitochondrial (mt) genome that have been modified by intragenomic rearrangements. In raptors, two noncoding regions are present: the CR has shifted to a new position with respect to the “ancestral avian gene order,” whereas the pseudo-control region (ΨCR) is located at the original genomic position of the CR. As possible mechanisms for this rearrangement, duplication and transposition have been considered. During characterization of the mt gene order in Bonelli's eagle Hieraaetus fasciatus, we detected intragenomic sequence similarity between the two regions supporting the duplication hypothesis. We performed intra- and intergenomic sequence comparisons in H. fasciatus and other falconiform species to trace the evolution of the noncoding mtDNA regions in Falconiformes. We identified sections displaying different levels of similarity between the CR and ΨCR. On the basis of phylogenetic analyses, we outline an evolutionary scenario of the underlying mutation events involving duplication and homogenization processes followed by sporadic deletions. Apparently, homogenization may easily occur if sufficient sequence similarity between the CR and ΨCR exists. Moreover, homogenization itself allows perpetuation of this continued equalization, unless this process is stopped by deletion. The Pandionidae and the Aquilinae seem to be the only two lineages of Falconiformes where homology between both regionsis still detectable, whereas in other raptors no similarity was found so far. In these two lineages, the process of sequence degeneration may have slowed down by homogenization events retaining high sequence similarity at least in some sections. |
Patrocinador/es: | Terra Natura Foundation; European Synthesys program; Grant number: AT-TAF-2434; Government of the Comunidad Valenciana; Spanish Ministry of Education and Science; Grant number: AP2001-1444. |
URI: | http://hdl.handle.net/10045/22724 |
ISSN: | 1552-5007 (Print) | 1552-5015 (Online) |
DOI: | 10.1002/jez.b.21282 |
Idioma: | eng |
Tipo: | info:eu-repo/semantics/article |
Derechos: | The definitive version is available at www3.interscience.wiley.com |
Revisión científica: | si |
Versión del editor: | http://dx.doi.org/10.1002/jez.b.21282 |
Aparece en las colecciones: | INV - ZV - Artículos Científicos |
Archivos en este ítem:
Archivo | Descripción | Tamaño | Formato | |
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2009_Journal_of_Experimental_Zoology_Part_B.pdf | Versión revisada (acceso abierto) | 485,81 kB | Adobe PDF | Abrir Vista previa |
2009_Journal_of_Experimental_Zoology_Part_B_final.pdf | Versión final (acceso restringido) | 218,52 kB | Adobe PDF | Abrir Solicitar una copia |
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