Radioprotective Effects from Propolis: A Review
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Título: | Radioprotective Effects from Propolis: A Review |
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Autor/es: | Ibáñez, Blanca | Melero, Ana | Montoro, Alegría | San Onofre Bernat, Nadia | Soriano, José M. |
Grupo/s de investigación o GITE: | Grupo Balmis de Investigación en Historia de la Ciencia, Cuidados en Salud y Alimentación (BALMIS) |
Centro, Departamento o Servicio: | Universidad de Alicante. Departamento de Enfermería Comunitaria, Medicina Preventiva y Salud Pública e Historia de la Ciencia |
Palabras clave: | Radioprotection | Propolis | Radiation |
Fecha de publicación: | 3-ago-2023 |
Editor: | MDPI |
Cita bibliográfica: | Ibáñez B, Melero A, Montoro A, San Onofre N, Soriano JM. Radioprotective Effects from Propolis: A Review. Molecules. 2023; 28(15):5842. https://doi.org/10.3390/molecules28155842 |
Resumen: | Propolis is a natural bee-produced substance with antimicrobial, anti-inflammatory, and wound-healing properties, containing some components from the leaves, buds and resins of plants. It has been used for centuries for various health benefits. In this manuscript, our group reviewed the radioprotective effect of propolis using PubMed and Embase, and our review was conducted according to the PRISMA statement. Finally, 27 articles were included in this review, which includes the radioprotective effect of propolis from cell-based studies (n = 8), animal models (n = 14), and human trials (n = 5). Results reflected that the dosage forms of propolis extracted in the scientific literature were ethanolic extracts of propolis, a water-soluble derivate of propolis, or capsules. The efficacy of the radioprotective properties from propolis is extracted from the bibliography, as several compounds of this resinous mixture individually or synergistically are possible candidates that have the radioprotective effect. In fact, studies prior to 2011 lacked a comprehensive characterization of propolis due to the variability in active compounds among different batches of propolis and were limited to analytical techniques. Furthermore, in this manuscript, we have selected studies to include primarily propolis types from Brazil, Croatia, Egypt, European countries, and those commercialized in Spain. They all contained ethanolic extract of propolis (EEP) and were influenced by different dosage forms. EEP showed a significant presence of lipophilic bioactive compounds like flavones, flavonols, and flavanones. |
Patrocinador/es: | This research was funded by The Spanish Nuclear Safety Council (2696/SRO). I.L. was supported by a Fellowship of the ‘University Junior International Entrepreneurs’ program (UJIE 2019) of University of Valencia and Generalitat Valenciana. N.S.O. was supported by the Universidad de Alicante, Ministerio de Universidades and the European Union “NextGeneration EU/PRTR” through 2022–2024 Margarita Salas grant (MARSALAS22-23). |
URI: | http://hdl.handle.net/10045/136801 |
ISSN: | 1420-3049 |
DOI: | 10.3390/molecules28155842 |
Idioma: | eng |
Tipo: | info:eu-repo/semantics/article |
Derechos: | © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
Revisión científica: | si |
Versión del editor: | https://doi.org/10.3390/molecules28155842 |
Aparece en las colecciones: | INV - BALMIS - Artículos de Revistas |
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Ibanez_etal_2023_Molecules.pdf | 2,07 MB | Adobe PDF | Abrir Vista previa | |
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