Gender Biases and Diagnostic Delay in Inflammatory Bowel Disease: Multicenter Observational Study
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Título: | Gender Biases and Diagnostic Delay in Inflammatory Bowel Disease: Multicenter Observational Study |
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Autor/es: | Sempere, Laura | Bernabeu, Purificación | Cameo, José | Gutierrez, Ana | García, María Gloria | García, Mariana Fe | Aguas, Mariam | Belén, Olivia | Zapater, Pedro | Jover, Rodrigo | van-der Hofstadt, Carlos | Ruiz-Cantero, María Teresa |
Grupo/s de investigación o GITE: | Salud Pública |
Centro, Departamento o Servicio: | Universidad de Alicante. Departamento de Enfermería Comunitaria, Medicina Preventiva y Salud Pública e Historia de la Ciencia |
Palabras clave: | Diagnostic delay | Inflammatory bowel disease | Gender biases | Misdiagnosis |
Fecha de publicación: | 31-ene-2023 |
Editor: | Oxford University Press |
Cita bibliográfica: | Inflammatory Bowel Diseases. 2023, 29(12): 1886-1894. https://doi.org/10.1093/ibd/izad001 |
Resumen: | Background: Female gender could be a cause of diagnostic delay in inflammatory bowel disease (IBD). The aim of this study was to investigate the diagnostic delay in women vs men and potential causes. Methods: This multicenter cohort study included 190 patients with recent diagnosis of IBD (disease duration <7 months). Reconstruction of the clinical presentation and diagnostic process was carried out in conjunction with the semistructured patient interview, review, and electronic medical records. Results: The median time from symptom onset to IBD diagnosis was longer in women than in men: 12.6 (interquartile range, 3.7-31) vs 4.5 (2.2-9.8) months for Crohn’s disease (CD; P = .008) and 6.1 (3-11.2) vs 2.7 (1.5-5.6) months for ulcerative colitis (UC; P = .008). Sex was an independent variable related to the time to IBD diagnosis in Cox regression analysis. The clinical presentation of IBD was similar in both sexes. Women had a higher percentage of misdiagnosis than men (CD, odds ratio [OR], 3.9; 95% confidence [CI], 1.5-9.9; UC, OR 3.0; 95% CI, 1.2-7.4). Gender inequities in misdiagnosis were found at all levels of the health system (emergency department, OR 2.4; 95% CI, 1.1-5.1; primary care, OR 2.5; 95% CI, 1.3-4.7; gastroenterology secondary care, OR 3.2; 95% CI, 1.2-8.4; and hospital admission, OR 4.3; 95% CI, 1.1-16.9). Conclusions: There is a longer diagnostic delay in women than in men for both CD and UC due to a drawn-out evaluation of women, with a higher number of misdiagnoses at all levels of the health care system. |
Patrocinador/es: | This study was supported by Instituto de Salud Carlos III (PI 18/01547), GETECCU (Grupo Español de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa, Grant 2017) and SVPD (Sociedad Valenciana de Patología Digestiva, Grant 2017). |
URI: | http://hdl.handle.net/10045/131781 |
ISSN: | 1078-0998 (Print) | 1536-4844 (Online) |
DOI: | 10.1093/ibd/izad001 |
Idioma: | eng |
Tipo: | info:eu-repo/semantics/article |
Derechos: | © 2023 Crohn’s & Colitis Foundation. Published by Oxford University Press on behalf of Crohn’s & Colitis Foundation. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
Revisión científica: | si |
Versión del editor: | https://doi.org/10.1093/ibd/izad001 |
Aparece en las colecciones: | INV - SP - Artículos de Revistas |
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