Occurrence of Volcanogenic Inorganic Mercury in Wild Mice Spinal Cord: Potential Health Implications
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http://hdl.handle.net/10045/117285
Title: | Occurrence of Volcanogenic Inorganic Mercury in Wild Mice Spinal Cord: Potential Health Implications |
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Authors: | Navarro-Sempere, Alicia | García, Magdalena | Rodrigues, Armindo S. | Garcia, Patrícia V. | Camarinho, Ricardo | Segovia, Yolanda |
Research Group/s: | Grupo de Inmunología, Biología Celular y del Desarrollo |
Center, Department or Service: | Universidad de Alicante. Departamento de Biotecnología |
Keywords: | Autometallography | Environmental pollutants | Heavy metals | Neurotoxicity | Mus musculus | Motor neurons | Axons | Motor neuron diseases |
Knowledge Area: | Biología Celular |
Issue Date: | 20-Aug-2021 |
Publisher: | Springer Nature |
Citation: | Biological Trace Element Research. 2022, 200: 2838-2847. https://doi.org/10.1007/s12011-021-02890-0 |
Abstract: | Mercury accumulation has been proposed as a toxic factor that causes neurodegenerative diseases. However, the hazardous health effects of gaseous elemental mercury exposure on the spinal cord in volcanic areas have not been reported previously in the literature. To evaluate the presence of volcanogenic inorganic mercury in the spinal cord, a study was carried out in São Miguel island (Azores, Portugal) by comparing the spinal cord of mice exposed chronically to an active volcanic environment (Furnas village) with individuals not exposed (Rabo de Peixe village), through the autometallographic silver enhancement histochemical method. Moreover, a morphometric and quantification analysis of the axons was carried out. Results exhibited mercury deposits at the lumbar level of the spinal cord in the specimens captured at the site with volcanic activity (Furnas village). A decrease in axon calibre and axonal atrophy was also observed in these specimens. Given that these are relevant hallmarks in the neurodegenerative pathologies, our results highlight the importance of the surveillance of the health of populations chronically exposed to active volcanic environments. |
Sponsor: | This research was supported by the University of Alicante VIGROB-186. |
URI: | http://hdl.handle.net/10045/117285 |
ISSN: | 0163-4984 (Print) | 1559-0720 (Online) |
DOI: | 10.1007/s12011-021-02890-0 |
Language: | eng |
Type: | info:eu-repo/semantics/article |
Rights: | © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
Peer Review: | si |
Publisher version: | https://doi.org/10.1007/s12011-021-02890-0 |
Appears in Collections: | INV - Grupo de Inmunología - Artículos de Revistas |
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File | Description | Size | Format | |
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Navarro-Sempere_etal_2022_BiolTraceElemRes.pdf | 1,42 MB | Adobe PDF | Open Preview | |
This item is licensed under a Creative Commons License