New method to improve the quality of vision in cataractous keratoconus eyes

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Título: New method to improve the quality of vision in cataractous keratoconus eyes
Autor/es: Miret, Juan Jose | Camps, Vicente J. | García Llopis, Celia | Caballero, María T. | Fez Saiz, Dolores de | Piñero, David P.
Grupo/s de investigación o GITE: Grupo de Óptica y Percepción Visual (GOPV) | Holografía y Procesado Óptico
Centro, Departamento o Servicio: Universidad de Alicante. Departamento de Óptica, Farmacología y Anatomía
Palabras clave: Intraocular lens | Keratoconus eyes | Quality of vision
Área/s de conocimiento: Óptica
Fecha de publicación: 18-nov-2020
Editor: Springer Nature
Cita bibliográfica: Scientific Reports. 2020, 10:20049. https://doi.org/10.1038/s41598-020-76977-4
Resumen: To analyze using optical simulations if the proper use of a segmented intraocular lens (IOL) can improve the visual outcomes compared to the implantation of a spherical monofocal IOL. The wavefront profile of the Mplus (Oculentis) and a monofocal IOLs with the phase transformation introduced by each IOL were calculated using a Hartmann-Shack wavefront sensor. In addition, the wavefront profile of schematic eye models of various keratoconus conditions was obtained and was propagated to the IOLs. The optical performance of such combination was obtained after combining ray tracing and Fourier optics. A pre-clinical validation was also evaluated incorporating clinical data from three different keratoconus eyes of three patients. The implantation of the Mplus IOL can compensate or reduce the overall coma of the eye with keratoconus improving the quality of vision compared with a spherical monofocal IOL due to lower displacements of the retinal image or tilting in keratoconus. All theoretical simulations were confirmed afterwards by mean of a preclinical validation. The use of a standard toric segmented IOL with a proper orientation and selection of the addition can improve the optical quality of the keratoconus eye compared to the use of a monofocal spherical IOL.
Patrocinador/es: David P. Piñero is supported by the Spanish Ministry of Economy, Industry and Competitiveness within the program Ramón y Cajal, RYC-2016-20471.
URI: http://hdl.handle.net/10045/110433
ISSN: 2045-2322
DOI: 10.1038/s41598-020-76977-4
Idioma: eng
Tipo: info:eu-repo/semantics/article
Derechos: © The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Revisión científica: si
Versión del editor: https://doi.org/10.1038/s41598-020-76977-4
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